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Table 1 Effects of ORCA2 overexpression on regulation of TIA and TIA-related biosynthetic genes and transcriptional regulators

From: The ORCA2 transcription factor plays a key role in regulation of the terpenoid indole alkaloid pathway

Transgene

Result

ASα

+

TDC

+

DXS

=

CPR

=

G10H

+

LAMT

+

STR

+

SGD

-

T16H

+

16OMT

=

D4H

+

DAT

-

PRX1

+

ZCT1

+

ZCT2

+

ZCT3

+

GBF1

=

GBF2

=

ORCA2

+

ORCA3

+

CrBPF1

=

CrMYC2

-

  1. “+” = up-regulation (transcript levels of indicated gene were higher at one or more time points when ORCA2 was overexpressed); “-” = down-regulation (transcript levels of indicated gene were lower at one or more time points when ORCA2 was overexpressed). “=” = no change (transcript levels of indicated gene were not significantly different when ORCA2 was overexpressed).