Characterization of paralogous protein families in rice

BMC Plant Biology

Table 2 Two-sample binomial tests for GOSlim assignments of paralogous family and singleton proteins in Arabidopsis

GOSlim assignment^a	Singletons (%)	Paralogous genes (%)	P-value^d
Hydrolase activity^b	7.5	12.6	<1e-5
Kinase activity^c	10.4	5.5	<1e-5
Nucleotide binding^c	10.2	4.6	<1e-5
Protein binding, other^c	12.9	8.2	<1e-5
Transcription factor activity^b	4.2	9.0	<1e-5
Receptor activity^c	1.9	0.7	<1e-5
DNA binding^b	4.1	7.2	<1e-5
Oxygen binding^b	0.1	1.4	<1e-5
Receptor binding^c	0.5	0.1	<1e-5
Carbohydrate binding^c	0.7	0.3	<1e-3
Lipid binding^b	0.3	0.8	0.001
Structural molecule activity^b	1.6	2.5	0.002
Enzyme regulator activity^b	0.7	1.4	0.005
Molecular function, other^b	1.8	2.5	0.011
Transporter activity^b	5.0	6.0	0.019
Nucleic acid binding, other^c	2.6	2.0	0.027
Motor activity^b	0.2	0.5	0.03
Transferase activity	5.3	6.1	0.053
RNA binding	1.5	1.9	0.099
Binding, other	12.3	11.3	0.102
Signal transducer activity	1.0	0.8	0.132
Catalytic activity, other	12.4	11.7	0.244
Transcription regulator activity	1.3	1.5	0.743
Chromatin binding	0.2	0.1	0.803
Translation factor activity, nucleic acid binding	0.6	0.6	1
Nuclease activity	0.7	0.8	1

^a GoSlim assignment classifications were performed as described in the Materials and Methods.
^b Enrichment of GOSlim annotations in paralogous protein families compared to singletons.
^c Reduction of GOSlim annotations in paralogous protein families compared to singletons.
^d Benjamini and Hochberg correction for multiple testing.

ISSN: 1471-2229