Table 4 Conserved domains in enzymes of C1 metabolism in maize, Arabidopsis, and E. coli

ZmSHMT1

1

SHMT

398

ZmMTHR1

1

MTHFR

297

AtSHMT1

1

SHMT

398

ZmMTHR2

1

MTHFR

266

EcGLYA

1

SHMT

378

AtMTHR1

1

MTHFR

295

ZmGCSH1

1

GCV_H

120

AtMTHR2

1

MTHFR

295

ZmGCSH2

1

GCV_H

120

EcMETF

1

MTHFR

280

ZmGCSH3

1

GCV_H

120

ZmMS1

2

Meth_synt_1

317

ZmGCSH4

1

GCV_H

99

Meth_synt_2

324

AtGCSH1

1

GCV_H

120

ZmMS2

2

Meth_synt_1

316

AtGCSH2

1

GCV_H

120

Meth_synt_2

324

AtGCSH3

1

GCV_H

120

ZmMS3

2

Meth_synt_1

316

EcGCSH

1

GCV_H

121

Meth_synt_2

324

ZmGCSP

2

GDC-P

428

AtMS1

2

Meth_synt_1

316

GDC-P

291

Meth_synt_2

324

AtGCSP1

2

GDC-P

427

AtMS2

2

Meth_synt_1

316

GDC-P

288

Meth_synt_2

324

AtGCSP2

2

GDC-P

428

AtMS3

2

Meth_synt_1

316

GDC-P

290

Meth_synt_2

324

EcGCSP

2

GDC-P

424

EcMETH

5

S-methyl_trans

311

GDC-P

354

Pterin_bind

212

ZmGCST

3

GCV_T

152

B12-binding

104

GCV_T_C

92

B12-binding_2

83

GCV_T

89

Met_synt_B12

273

AtGCST

2

GCV_T

215

ZmFTHS

1

FTHFS

620

GCV_T_C

92

AtFTHS

1

FTHFS

620

EcGCST

2

GCV_T

208

ZmPURU

1

Formyl_trans_N

178

GCV_T_C

92

AtPURU1

1

Formyl_trans_N

178

ZmFOLD1

2

THF_DHG_CYH

117

AtPURU2

1

Formyl_trans_N

178

THF_DHG_CYH_C

167

EcPURU

1

Formyl_trans_N

177

ZmFOLD2

2

THF_DHG_CYH

117

Zm5FCL

1

5-FTHF_cyc-lig

205

THF_DHG_CYH_C

105

At5FCL

1

5-FTHF_cyc-lig

203

ZmFOLD3

2

THF_DHG_CYH

117

Ec5FCL

1

5-FTHF_cyc-lig

175

THF_DHG_CYH_C

167

Zm5FCLL

1

5-FTHF_cyc-lig

101

AtFOLD1

2

THF_DHG_CYH

117

At5FCLL

1

5-FTHF_cyc-lig

198

THF_DHG_CYH_C

167

AtFOLD2

2

THF_DHG_CYH

117

THF_DHG_CYH_C

167

AtFOLD3

2

THF_DHG_CYH

53

THF_DHG_CYH_C

167

AtFOLD4

2

THF_DHG_CYH

117

THF_DHG_CYH_C

167

EcFOLD

2

THF_DHG_CYH

117

THF_DHG_CYH_C

159