Fig. 7

Confocal z-projections showing cells adapting their shape to interact with the fibrous environment. a An overview. b-h Higher resolution examples of cell shapes.White arrows indicate small round cells. Yellow arrows indicate cell-fibre interaction. Red asterisks in a-b indicate heterogeneous growth between neighbouring cells, demonstrating the ability of the cells to slip past each other and continue elongation, a behaviour unobserved in native tissues. GFP-labelled microtubules in cells expressing reporter construct 35S::GFP-MBD. Scale bars: 100 μm