Fig. 7
From: Dissection of MAPK signaling specificity through protein engineering in a developmental context
MKK5 defines a cluster of chimeras with low activity at FAMA stage, whereas clustering and inhibiting chimeras group in two independent clusters. a SPCH and FAMA stage activities show a weak positive correlation. Shaded area corresponds to activities at the FAMA stage lower than 30%. Data points are colored according to the cluster they belong to in (b). MKK activities at the FAMA stage are separated into three clusters (b): cluster 1 contains MKKs that show no phenotypic effect and contain loop 5B; cluster 2 contains MKKs that lead to stomatal clustering and contain N7; and, cluster 3 contains MKKs that lead to inhibition of stomatal development and contain loop 7B. Numbers next to nodes correspond to approximately unbiased p-values with bootstrap replications set to 1000. Chimeras not significantly different in Chi-squared tests if independence are indicated with an identical number (p > 0.05)