Fig. 5

The possible regulatory network of the gene expression in response to the loss of function of POCO1 in mitochondria. Loss of function of POCO1 is sensed by mitochondria. Subsequently, a retrograde signaling cascade may be activated to launch the gene expression changes. Several transcription factors, which control stress-inducible gene expression are affected. Several processes may be under the influence of defected ABA signaling in poco1. Black lines indicate crosstalk and differential regulation. Dashed arrows are indicative of possible inhibiting effects