Table 2 Group and sub-group specific conserved motifs

1

L[RK]MGIDPVTH[ST]PRLDLLD[IL]SSIL[NRS][SA]S[LFI][YG][NG]

2

[AHY][ANS][NY][DS][SK]N[FY][DN]D[GD]M[DE]FW[YF]D[IV][FL][TAI][RKS][ST][GN][ED][SI]IEL[LPS]E

3

[EP][ETD][INTV][MN][PAL][APV][IL]DE[SD]FWSE[VA][LAT][SIV][DS][DY][EN]

4

[KD][PK][NP]xL[IL]EIP[FW][DE][LPS]D[HPY]D[FI]W[SK][FL][LI]D

5

PKL[LF]F[SA]EWL

6

[HIK][KV][AK][PS][SAE]S[PT]STRHM[AV]QWES[AV]R[LV]EAEARLS[RN]E

7

[SY]W[NP][NT][NS]KT[DC][SP]D[HY]FL[RQ][IL]WNSEVG[EK][SA]FR[DMN][VI][HK][GK]

8

D[TS][AS]L[QK][LH]LL[DH][FM]P[ID][NS][ND][DM]

9

[RK]GQWERRLQTDI[NH]MAK[QKR]AL[SC]EALS[PL][DN]K[PA]

10

[PT][TN][TP][TY][QP][ST][GMT][CTV]YASS[AT][DE]NIA[RK]LL[KQ][GN][WF]MK[ND][TS]PK

11

[QD][GM][PS][FL]SL[FL]EKWL[FL]D[DE][QA][GAS][CGH]Q[EMQ]

12

[KT]N[DE][AT]LLS[ST][DEL]G[QP]SK[DNT]AANLSHMAQWESARLEAEARL[VA]RESK[LI]

13

[IT]T[SV]N[AV][GT][RV][SV][GQS][DQ]LESPTST[LV]S[FE][SN][EN]N[AV]P[MPS]

14

[DN][LFY]YE[DE]N[KN]NYWN[SN]I[LF]NL[VM][ND][SY]S[PS]

15

GIG[LP][EQ][KS]DNIRDPL[EV]PNLTSPSHS[IV]TSAKLLNKMATSLPHKV[HY]GLEA[AV]KAVFSKLME

16

[FQ]VG[GS]CLNALSPFED[GK]PHI[ST]K[IT]IDSPS[GS]PTLMFN[HQ]VTTPSCFSEDNEDNWQCVSSNYVSF[KR][IN]CAA[NS]GG

17

[LG][GM][AH]Q[APY][LV][VM]NPE[LFI]LKLA

18

S[VE][LS][SV]TP[SL]S[ST]PTPLNS

19

[YFIS][VNS][NG][SCG][SNT]TE[DE]ER[DE][STQ][YS][CYG][SD]

20

[LQ]A[ELR][ALQ][QTV][EQ][LM]AKLQ[YCL][LF][QH][YQ]

21

[NY][AGV][EG][DG][ANP][SC][ST][YI]W[PS][ED][LH]L[LF][ED]

22

[EF][EL][MT]WGDFM[DY]EE

23

KT[QL]VYLPKPIRVKA[ML][YS][LS][QC][RI][TP][DR]

24

HG[TN]L[QE][QK]LYEEY[FL]QLLN[MV][DE][EHQ][GK][QP][FD]E[LR][ND]SFA[EQ]SLL

25

[PYL][NG][HFNQ][DQT][NE][ND][LQV][QTE][TA][KN][PI][PK][VIM]QE[TA][LF]FS[SH][TK][CP]PLF[MI][FV]DT

26

[FL][EG][SP][VN][NK][IM]G[VAL][EG]GD[FM][SYF][VL]P[PS]LE[SN][RV][ST][ICT][ET][SR][ND]

27

[EIV][ELS]E[RP][CH][PH][DQ]LNL[ED]L[SRT]I[SG][PL]P[SRW]Q[PQ]Q

28

ERCPDLNLEL[RT]ISPP[RW]QQQ

29

CF[AV]C[SR][LF]G[LM]HN[SG][KM][DE]C[SR]

30

[LF]DMK[GK]I[IM][ANS]LLE[DE][ND]NHRVP[SY]IS

31

M[HY][APQ][NA][TC][ST][EP][ER][QK]GY[FL]Y[SN]M[FV][NI][PV][NF][CD]

32

[WF][EG][LV][GMR][SK]SPYE[TN]RI[LS]DWI[AS]E[LI][QS][NT][GD][YQ][GS][ED][AKN][EN]L[ES][QE]D[CH][NS]S[TN][GS][TC][CS][NE][NY][YN]

33

NYWS[MI][ED]DIWS[MS]

34

W[TND][DV]E[NS][MFI][WLC][FL]LQQ

35

[NS]SGLLD[AD]LLEEA[QEK]A[LM][SA]S[GS][KEG][NK]SK[KS][DR][KR]S

36

GHRA[LW][AG][TD]HKKEAAWRL[SR]R[VL]ELQLESEK[TA][NC]R[RQ]REK[IM]EE[FI]EAK[IM]KAL[QR]EE[EQ][KL][AN]A[LM][GE][RK]IE[AG]EYREQL[ADV][AG]LRRDAE[NA]K[ED]QKLA

37

[LV][FHY]RPV[AP]R[VLM][SG][AS]F[SN][VAI][YC][NHK]

38

[CDY][CDGSY][ED][PQR][FIMQS][VI]P[SHQ][KQT]CG[HG]GC[CS]

39

[EA][LF][IA][SA]I[AS][TN][DE][LI][NGS][NS][ILT]AW[IL][KR]SG[LK][ED]

40

[ET]T[SA]SS[SE]DDP[PA]TSLSLSLPG[VAF]D

41

F[SG][GA]EF[ML][AT]V[MV]QEMI[RK]KEVRSYM[SAE]x[ML][QE][QR][GN]NG

42

[PKV][RG][PN][NS][IL]L[EQ][DN]YI[KR]S[IL][TNE][ILQ][NI]

43

[RM][LV][SI]RVELQLESEK[AT][GN]RRREK[IM]EE[FI]EAKIKAL[QR]EE[EQ][TKL]AAL[DG]RIEAEYREQL[AD][AG]LRRDAE[NS]KEQKLAEQW[AD]AKHLR[LF]T[KR][FL]LEQ[LSV][GD][CT][RI]

44

RIGMTPTRDGFSFSMTPKGTPLRD[AE]LHINEDMNMHDSTKLELQRQADMRRSLRSGLGSLPQPKNEYQIVM[PQ]PV[LP]EDAEEPEEKIEEDMSDRIAREKAEEEARQQALLRKRSKVLQRELPRPPTASLELIRNSLMRTD[GV]DKSSFVPPTSIEQADEMIRRELL[ST]LLEHDN[AG]KYPLD[DE]KVIKEKKKGAKRAVNGSAVPVIEDF[EQ]EDEMKEADKLIKEEALYLCAAMGHEDEPLDEFIEAHRTCLNDLMYFPTR

45

A[QE]NNKIQGTFLKKDDPK[IV][NST]ALMQQAELLSSLA[LQ]KV[DN]A[ED]N[MT]DQS[LM]ENAWKVLQ[ED]FLN[RK][TS]KE[SN]D[IL][PF][RG][YQ][KG]IPD

46

[LF]QLV[DE][LF]KDL[IL][EA]DL[KR]S[GS][NS]E[ED][GI]Q[AP][CS]WRQ[MPV][DE]L[YH

47

[EK]FSSP[LI]QVTPLFRSLA[AD]GIPSPQFSESER[SN]FL[MRL]KTLG[MI]ES[PS]S[ILP][NC]PS[AV]N[PS]S[QK]PP[PL]CKR[AV]LL[IPH]

48

GIDYNAEIPFEKR[PA]P[PA]GF[FY]D[VT][TA]DEDRP[VA][ED]Q[PV][QK]FPTTIEELEGKRR[VA]DVEA[QH]LRKQD[IV]A[KR]NKIAQRQDAP[SA]AIL[HQ]ANKLNDPE[TV]VRKRSKLMLPPPQISD[QH]

49

KGDAIMMEAENLARLR[ED]SQTPLLGGENPELHPSDF[NST]GVTP[KR]KKEIQTPNPMLTPS[AM]TPG[GA]AGLTPRIG[ML]TP[TS]RDG[FS]SFSMTPKGTP[LF]RD[EA]LHINEDM[ND]MH

50

I[ED]DF[DEQ]E[DN]E[ML][KQ]EADK[LM]IKEE[AG][LK][YF]LC[AV][AS]MGHE[DN][EK][PT]LD[ED]F[IV]EAH[RN]TC[LV]NDLMYFPTR[NS]AY[GE]LSSVAGN[MA][ED]K[LV][AT]A[LF]Q[NE]E[FM]ENVR