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Figure 8 | BMC Plant Biology

Figure 8

From: Bikinin-like inhibitors targeting GSK3/Shaggy-like kinases: characterisation of novel compounds and elucidation of their catabolism in planta

Figure 8

The catabolic fate of compound 10 in A. thaliana. Compound 10 is rapidly hydrolysed, likely by a lipase, and thereby activated to compound 15. Subsequently, compound 15 is inactivated by conjugation with glutamic acid or with malate. The latter reaction is catalysed by SNG1. Since SNG1 utilises glucosylated substrates compound 15 is presumably glucosylated by a UGT prior to SNG1-mediated conjugation with malate.

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