Enrichment of edges joining genes from the same pathway in the graph in Fig. 2B (red arrow), as compared to random graphs (blue histogram). Histogram shows distribution of numbers of links joining genes from the same pathway in each of 10,000 random graphs with the same links structure as the original graph (μ = 111.7; σ = 6.8). Red arrow denotes number of within-pathway links (245) based on expression data (from Fig. 2B graph), blue arrow denotes mean number of within-pathway links (111.7) in randomly obtained graphs. Total number of links in each graph is 444.